ニュース
2月4日 業績を更新しました
原著論文(英文)
2010年
1. Yamada T, Matsumoto K, Wang W, Li Q, NishiokaY, Sekido Y, Sone S, Yano S.
Hepatocyte growth factor reduces susceptibility to irreversible epidermal growth factor receptor inhibitor in EGFR-T790M mutant lung cancer.
Clin Cancer Res 16:174-183, 2010.
2009年
1.Wang W, Li Q, Yamada T, Matsumoto K, Matsumoto I, Oda M, Watanabe G, Kayano Y, Nishioka Y, Sone S, Yano S.
Crosstalk to stromal fibroblasts induces resistance of lung cancer to EGFR tyrosine kinase inhibitors.
Clinical Cancer Res 15:6630-6638, 2009.
2.Yamada T, Ohtsubo K, Mouri H, Yamashita K, Yasumoto K, Izumi K, Zen Y, Watanabe H, Yano S.
Combined chemotherapy with carboplatin plus irinotecan showed favorable efficacy in a patient with relapsed small cell carcinoma of the prostate complicated with meningeal carcinomatosis.
Int J Clin Oncol 14:468-472, 2009.
3.Ohtsubo K, Watanabe H, Tsuchiyama T, Mouri H, Yamaguchi Y, Motoo Y, Okai T, Sanada J, Matsui O, Kitamura T, Fujiki R, Tokuuye K, Sawabu N.
A case of advanced hepatocellular carcinoma treated effectively with irinotecan via hepatic arterial infusion followed by proton beam therapy.
J Infect Chemother 15:316-321, 2009.
4. Ohtsubo K, Watanabe H, Yamada T, Tsuchiyama T, Mouri H, Yamashita K, Yasumoto K, Ikeda H, Nakanuma Y, Yano S.
Cancer of unknown primary site in which tumor marker-oriented chemotherapy was effective and pancreatic cancer was finally confirmed at autopsy.
Intern Med 48:1651-1656, 2009.
5. Ikuta K, Yano S, Trung TV, Hanibuchi M, Goto H, Li Q, Wang W, Yamada T, Ogino H, Kakiuchi S, Uehara H, Sekido Y, Uenaka T, Nishioka Y, Sone S.
E7080, a multi-tyrosine kinase inhibitor, suppresses the progression of malignant pleural mesothelioma with different proangiogenic cytokine production profiles.
Clin Cancer Res15:7229-7237, 2009.
6. Yamada T, Muguruma H, Yano S, Ikuta K, Ogino H, Kakiuchi S, Hanibuchi M, Uehara H, Nishioka Y, Sone S.
Intensification therapy with anti-parathyroid hormone-related protein antibody plus zoledronic acid for bone metastases of small cell lung cancer cells in SCID mice.
Mol Cancer Ther 8:119-126, 2009.
7. Wang W, Nishioka Y, Ozaki S, Jalili A, Verma VK, Hanibuchi M, Abe S, Minakuchi K, Matsumoto T, Sone S.
HM1.24 (CD317) is a novel target against lung cancer for immunotherapy using anti-HM1.24 antibody chimeric and humanized anti-HM1.24 antibodies mediate antibody-dependent cellular cytotoxicity against lung cancer cells.
Lung Cancer 63:23-31, 2009.
2008年
1. Wang W, Nishioka Y, Ozaki S, Jalili A, Abe S, Kakiuchi S, Kishuku M, Minakuchi K, Matsumoto T, Sone S.
HM1.24 (CD317) is a novel target against lung cancer for immunotherapy using anti-HM1.24 antibody.
Cancer Immunol Immunother 58(6):967-76. 2008
2. Kitagawa H, Ohta T, Makino I, Tani T, Tajima H, Nakagawara H, Ohnishi I, Takamura H, Kayahara M, Watanabe H, Gabata T, Matsui O, Zen Y.
Carcinomas of the ventral and dorsal pancreas exhibit different patterns of lymphatic spread.
Frontiers in Bioscience 13:2728-2735, 2008.
3. Ohtsubo K, Watanabe H, Okada G, Tsuchiyama T, Mouri H, Yamaguchi Y, Motoo Y, Okai T, Amaya K, Kitagawa H, Ohta T, Gabata T, Matsuda K, Ohta H, Sawabu N.
A case of pancreatic cancer with formation of a mass mimicking alcoholic or autoimmune pancreatitis in a young man. Possibility of diagnosis by hypermethylation of pure pancreatic juice.
JOP 9:37-45, 2008.
4.Ogino H, Yano S, Kakiuchi S, Muguruma H, Ikuta K, Uehara H, Tsuchida K, Sugino H, Sone S.
Follistatin suppresses the production of experimental multiple-organ metastasis by small cell lung cancer cells in NK cell-depleted SCID mice.
Clin Cancer Res 14:660-667, 2008.
5.Ogino H, Yano S, Kakiuchi S, Yamada T, Ikuta K, Nakataki E, Goto H, Nishioka Y, Ryan A, Sone S.
Novel dual targeting strategy with vandetanib induces tumor cell apoptosis and inhibits angiogenesis in malignant pleural mesothelioma cells expressing RET oncogenic rearrangement.
Cancer Letter 265:55-66, 2008.
6.Yamada T, Yano S, Ogino H, Ikuta K, Kakiuchi S, Hanibuchi M, Taniguchi, Sekido Y, Sone S.
Lysophosphatidic acid stimulates the proliferation and motility of malignant pleural mesothelioma cells through lysophosphatidic acid receptors, LPA1 and LPA2.
Cancer Sci 99:1603–1610, 2008.
7.Yano S, Wang W, Li Q, Matsumoto K, Sakurama H, Nakamura T, Ogino H, Kakiuchi S, Hanibuchi M, Nishioka Y, Uehara H, Mitsudomi T, Yatabe Y, Nakamura T, Sone S.
Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma cells with EGF receptor mutations.
Cancer Res 66:9479-9487, 2008.
8.Kitagawa H, Ohta T, Makino I, Tani T, Tajima H, Nakagawara H, Ohnishi I, Takamura H, Kayahara M, Watanabe H, Gabata T, Matsui O, Zen Y.
Carcinomas of the ventral and dorsal pancreas exhibit different patterns of lymphatic spread.
Frontiers in Bioscience 13, 2728-35, 2008.
2007年
1.Li Q, Yano S, Ogino H, Wang W, Uehara H, Nishioka Y, Sone S.
The therapeutic efficacy of anti-vascular endothelial growth factor antibody, bevacizumab, and pemetrexed against orthotopically implanted human pleural mesothelioma cells in SCID mice.
Clin Cancer Res 13:5918-25, 2007.
2.Tomimoto H,Yano S, Muguruma H, Kakiuchi S, Sone S.
Levels of soluble vascular endothelial growth factor receptor 1 are elevated in the exudative pleural effusions.
J Med Invest 54:146-53, 2007.
3.Tsuchiyama T, Nakamoto Y, Sakai Y, Marukawa Y, Kitahara M, Mukaida N, Kaneko S.
Prolonged, NK cell-mediated antitumor effects of suicide gene therapy combined with monocyte chemoattractant protein-1 against hepatocellular carcinoma.
J Immunol 178: 574-83, 2007.
4.Ohtsubo K, Watanabe H, Tsuchiyama T, Mouri H, Yamaguchi Y, Motoo Y, Ohnishi I, Gabata T, Sawabu N.
A case of autoimmune pancreatitis associated with retroperitoneal fibrosis.
J Pancreas 8: 320-5, 2007.
5.Koizumi K, Yasumoto K, et al.
Chemokine receptors expressed on cancer cells and chemokines derived from cancer cells: Their roles in cancer metastasis and progression.
Cancer Sci 98:1652-8, 2007.
6.Kitakata S, Yasumoto K, et al.
A case of primary small cell carcinoma of the breast.
Breast Cancer 14:414-7, 2007.
7.Yamashita K, Ougolkov AV, Nakazato H, Ito K, Ohashi Y, Kitakata H, Yasumoto K, Omote K, Mai M, Takahashi Y, Minamoto T.
Adjuvant immunochemotherapy with protein-bound polysaccharide K for colon cancer in relation to oncogenic beta-catenin activation.
Dis Colon Rectum 50:1169-81, 2007
8.Sone S,Yano S.
Molecular pathogenesis and its therapeutic modalities of lung cancer metastasis to bone.
Cancer Metastasis Rev 26:685-9, 2007.
原著論文(和文)
2008年
1. 毛利久継、土山智也、大坪公士郎、萱原正都、太田哲生、北川 諭など.
Octreotide投与下に5-FU少量持続静注を行い、著明なQOLの改善をみたperformance status不良の膵癌癌性腹膜炎の1剖検例.
日本消化器病学会雑誌 105:152-35, 2008.
2007年
1.大坪公士郎、渡邊弘之、土山智也、毛利久継、山口泰志、澤武紀雄.
シアノアクリレートを用いた予防的内視鏡的硬化療法が有用であった孤立性胃静脈瘤の4例.
Endoscopic Forum for digestive disease 23 : 19-24, 2007.
研究業績へ
2010年
1. Yamada T, Matsumoto K, Wang W, Li Q, NishiokaY, Sekido Y, Sone S, Yano S.
Hepatocyte growth factor reduces susceptibility to irreversible epidermal growth factor receptor inhibitor in EGFR-T790M mutant lung cancer.
Clin Cancer Res 16:174-183, 2010.
2009年
1.Wang W, Li Q, Yamada T, Matsumoto K, Matsumoto I, Oda M, Watanabe G, Kayano Y, Nishioka Y, Sone S, Yano S.
Crosstalk to stromal fibroblasts induces resistance of lung cancer to EGFR tyrosine kinase inhibitors.
Clinical Cancer Res 15:6630-6638, 2009.
2.Yamada T, Ohtsubo K, Mouri H, Yamashita K, Yasumoto K, Izumi K, Zen Y, Watanabe H, Yano S.
Combined chemotherapy with carboplatin plus irinotecan showed favorable efficacy in a patient with relapsed small cell carcinoma of the prostate complicated with meningeal carcinomatosis.
Int J Clin Oncol 14:468-472, 2009.
3.Ohtsubo K, Watanabe H, Tsuchiyama T, Mouri H, Yamaguchi Y, Motoo Y, Okai T, Sanada J, Matsui O, Kitamura T, Fujiki R, Tokuuye K, Sawabu N.
A case of advanced hepatocellular carcinoma treated effectively with irinotecan via hepatic arterial infusion followed by proton beam therapy.
J Infect Chemother 15:316-321, 2009.
4. Ohtsubo K, Watanabe H, Yamada T, Tsuchiyama T, Mouri H, Yamashita K, Yasumoto K, Ikeda H, Nakanuma Y, Yano S.
Cancer of unknown primary site in which tumor marker-oriented chemotherapy was effective and pancreatic cancer was finally confirmed at autopsy.
Intern Med 48:1651-1656, 2009.
5. Ikuta K, Yano S, Trung TV, Hanibuchi M, Goto H, Li Q, Wang W, Yamada T, Ogino H, Kakiuchi S, Uehara H, Sekido Y, Uenaka T, Nishioka Y, Sone S.
E7080, a multi-tyrosine kinase inhibitor, suppresses the progression of malignant pleural mesothelioma with different proangiogenic cytokine production profiles.
Clin Cancer Res15:7229-7237, 2009.
6. Yamada T, Muguruma H, Yano S, Ikuta K, Ogino H, Kakiuchi S, Hanibuchi M, Uehara H, Nishioka Y, Sone S.
Intensification therapy with anti-parathyroid hormone-related protein antibody plus zoledronic acid for bone metastases of small cell lung cancer cells in SCID mice.
Mol Cancer Ther 8:119-126, 2009.
7. Wang W, Nishioka Y, Ozaki S, Jalili A, Verma VK, Hanibuchi M, Abe S, Minakuchi K, Matsumoto T, Sone S.
HM1.24 (CD317) is a novel target against lung cancer for immunotherapy using anti-HM1.24 antibody chimeric and humanized anti-HM1.24 antibodies mediate antibody-dependent cellular cytotoxicity against lung cancer cells.
Lung Cancer 63:23-31, 2009.
2008年
1. Wang W, Nishioka Y, Ozaki S, Jalili A, Abe S, Kakiuchi S, Kishuku M, Minakuchi K, Matsumoto T, Sone S.
HM1.24 (CD317) is a novel target against lung cancer for immunotherapy using anti-HM1.24 antibody.
Cancer Immunol Immunother 58(6):967-76. 2008
2. Kitagawa H, Ohta T, Makino I, Tani T, Tajima H, Nakagawara H, Ohnishi I, Takamura H, Kayahara M, Watanabe H, Gabata T, Matsui O, Zen Y.
Carcinomas of the ventral and dorsal pancreas exhibit different patterns of lymphatic spread.
Frontiers in Bioscience 13:2728-2735, 2008.
3. Ohtsubo K, Watanabe H, Okada G, Tsuchiyama T, Mouri H, Yamaguchi Y, Motoo Y, Okai T, Amaya K, Kitagawa H, Ohta T, Gabata T, Matsuda K, Ohta H, Sawabu N.
A case of pancreatic cancer with formation of a mass mimicking alcoholic or autoimmune pancreatitis in a young man. Possibility of diagnosis by hypermethylation of pure pancreatic juice.
JOP 9:37-45, 2008.
4.Ogino H, Yano S, Kakiuchi S, Muguruma H, Ikuta K, Uehara H, Tsuchida K, Sugino H, Sone S.
Follistatin suppresses the production of experimental multiple-organ metastasis by small cell lung cancer cells in NK cell-depleted SCID mice.
Clin Cancer Res 14:660-667, 2008.
5.Ogino H, Yano S, Kakiuchi S, Yamada T, Ikuta K, Nakataki E, Goto H, Nishioka Y, Ryan A, Sone S.
Novel dual targeting strategy with vandetanib induces tumor cell apoptosis and inhibits angiogenesis in malignant pleural mesothelioma cells expressing RET oncogenic rearrangement.
Cancer Letter 265:55-66, 2008.
6.Yamada T, Yano S, Ogino H, Ikuta K, Kakiuchi S, Hanibuchi M, Taniguchi, Sekido Y, Sone S.
Lysophosphatidic acid stimulates the proliferation and motility of malignant pleural mesothelioma cells through lysophosphatidic acid receptors, LPA1 and LPA2.
Cancer Sci 99:1603–1610, 2008.
7.Yano S, Wang W, Li Q, Matsumoto K, Sakurama H, Nakamura T, Ogino H, Kakiuchi S, Hanibuchi M, Nishioka Y, Uehara H, Mitsudomi T, Yatabe Y, Nakamura T, Sone S.
Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma cells with EGF receptor mutations.
Cancer Res 66:9479-9487, 2008.
8.Kitagawa H, Ohta T, Makino I, Tani T, Tajima H, Nakagawara H, Ohnishi I, Takamura H, Kayahara M, Watanabe H, Gabata T, Matsui O, Zen Y.
Carcinomas of the ventral and dorsal pancreas exhibit different patterns of lymphatic spread.
Frontiers in Bioscience 13, 2728-35, 2008.
2007年
1.Li Q, Yano S, Ogino H, Wang W, Uehara H, Nishioka Y, Sone S.
The therapeutic efficacy of anti-vascular endothelial growth factor antibody, bevacizumab, and pemetrexed against orthotopically implanted human pleural mesothelioma cells in SCID mice.
Clin Cancer Res 13:5918-25, 2007.
2.Tomimoto H,Yano S, Muguruma H, Kakiuchi S, Sone S.
Levels of soluble vascular endothelial growth factor receptor 1 are elevated in the exudative pleural effusions.
J Med Invest 54:146-53, 2007.
3.Tsuchiyama T, Nakamoto Y, Sakai Y, Marukawa Y, Kitahara M, Mukaida N, Kaneko S.
Prolonged, NK cell-mediated antitumor effects of suicide gene therapy combined with monocyte chemoattractant protein-1 against hepatocellular carcinoma.
J Immunol 178: 574-83, 2007.
4.Ohtsubo K, Watanabe H, Tsuchiyama T, Mouri H, Yamaguchi Y, Motoo Y, Ohnishi I, Gabata T, Sawabu N.
A case of autoimmune pancreatitis associated with retroperitoneal fibrosis.
J Pancreas 8: 320-5, 2007.
5.Koizumi K, Yasumoto K, et al.
Chemokine receptors expressed on cancer cells and chemokines derived from cancer cells: Their roles in cancer metastasis and progression.
Cancer Sci 98:1652-8, 2007.
6.Kitakata S, Yasumoto K, et al.
A case of primary small cell carcinoma of the breast.
Breast Cancer 14:414-7, 2007.
7.Yamashita K, Ougolkov AV, Nakazato H, Ito K, Ohashi Y, Kitakata H, Yasumoto K, Omote K, Mai M, Takahashi Y, Minamoto T.
Adjuvant immunochemotherapy with protein-bound polysaccharide K for colon cancer in relation to oncogenic beta-catenin activation.
Dis Colon Rectum 50:1169-81, 2007
8.Sone S,Yano S.
Molecular pathogenesis and its therapeutic modalities of lung cancer metastasis to bone.
Cancer Metastasis Rev 26:685-9, 2007.
原著論文(和文)
2008年
1. 毛利久継、土山智也、大坪公士郎、萱原正都、太田哲生、北川 諭など.
Octreotide投与下に5-FU少量持続静注を行い、著明なQOLの改善をみたperformance status不良の膵癌癌性腹膜炎の1剖検例.
日本消化器病学会雑誌 105:152-35, 2008.
2007年
1.大坪公士郎、渡邊弘之、土山智也、毛利久継、山口泰志、澤武紀雄.
シアノアクリレートを用いた予防的内視鏡的硬化療法が有用であった孤立性胃静脈瘤の4例.
Endoscopic Forum for digestive disease 23 : 19-24, 2007.
研究業績へ
